Products & Services / Instruments and equipment

DASEA® Regenbio automated 3D cell culture bioreactor

DASEA® Regenbio automated 3D cell culture bioreactor is an independently developed bioreactor, with Digitalized, Automated, Scalable, Enclosed, and Activated (DASEA®) features. It is equipped with a human-machine interface (HMI) ecosystem, enabling simplified and efficient operation. The bioreactor utilizes a medium to large scale PLC master control system for precise control and comprehensive functionality, supporting customization. The bioreactor ensures a safe cell culture process with its precise parameter control and powerful data management capabilities, is suitable for large-scale culture of MSC, T, CHO and other cells.
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Advantages

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Gentle
Elephant ear impeller
Low shear force, low cell injur
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Uniform
Uniform flow field distribution
No dead zone accumulation
Efficient mass transfer
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Steady
Precise PID control strategy ensures gentle fluctuations in temperature, pH, and DO, bringing the culture environment closer to a steady state.
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Automated
Independently developed core control system ensures efficient linkage, precise control, and comprehensive functions, supporting customzied needs for cell culture process.

Features

· Elephant ear impeller: Designed based on CFD fluid simulation, low shearing, low cell injury.
· Gas exchange strategy: Both surface and internal aeration, fulfill different process requirements.
· Dedicated micro bubbles: Micro bubble design to increase gas-liquid contact area for efficient mass transfer.
· Froward and reverse stirring: Meets the needs of various liquid mixing processes, adjustable forward and reverse switching speed and smoothness.
· Magnetic coupling motor: No mechanical sealing structure, good airtightness, safe and reliable.
· Expandable vessel lid: Supports customization to meet diverse customer needs.
· Easy calibration: Supports calibration of temperature, pH, and DO sensors, and automatic recording.
· Power outage protection: Automatically restores data and resumes operation from pre-outage state.
· Diverse modes and recipes: Multiple modes and control through recipes to achieve varied process requirements.
· Multi-level access mangement: Available to setup mutiple level user access.
· Audit trail: GMP compliance, ensuring data integrity and traceability.
· HMI: Independently developed human-machine interface for easy operation.

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