app.png
Solutions

The strategic process of the DASEA Bio-Manufacturing platform “Intelligentized -- Digitalized -- AI"

Through its innovative platform, REGEN-αGEEK has achieved fully automated and large-scale production of cells and exosomes, pushing the boundaries of regenerative medicine.

DASEA Bio-manufacturing Platform
Building the core “new productive capacity” in the CGT

Bottlenecking problems of 2D cell culture technology

Advantages of DASEA Bio-Manufacturing platform

Poor Quality Control

Subjective indicators, experience dependent

Digitalized

digitalization of whole process and consumables

High Fabrication Cost

labor intensive, low utilization rate of consumables

Automated

automatic and programable process control

Low Production Efficiency

insufficient use of space

Scalable

3D culture, large single-batch production yield

High Contamination Risk

open space operation

Enclosed

enclosed system, less contamination

Reduced Cellular Activity

Repeated enzyme digestion

Activated

better cell activity with biomimetic microcarriers

Cost Comparison — DASEA 3D vs 2D

Expected cell harvest

Type of cultivation

Facility

Time

Labor

Reagent & consumables (thousand yuan)

Total cost (thousand yuan)

1*1010cells

2D

200㎡

1200h

10人

19.53

28.32

DASEA 3D

100㎡

120h

1人

9.60

13.30

app2.png

90

%

Facility

app2.png

90

%

Labour

app3.png

80

%

Time

app4.png

52

%

Reagents & Consumables

app5.png

62

%

Total Cost

DASEA Solution for Stem Cell Large-scale Production

三维干细胞大规模制备应用方案-英文-02.jpg

Bio-manufacturing of Mesenchymal Stem Cells (DASEA 3D vs 2D)

01

Basic Biological Properties

Cell morphology / Viability / Cell count

Surface marker analysis of hUMSCs

Human STR profiling identification

Induced in vitro differentiation capacity test (Tri-lineage differentiation)

Chromosomal karyotyping

02

Biological Safety

Telomerase activity assay

Soft agar colony formation assay

Nude mouse inoculation test

03

Microbiological safety

Bacterial/Fungal detection

Mycoplasma detection

Adventitious virus testing (Human / Animal-derived)

Endotoxin testing

Lysate residue

Microcarrier lysate residue testing

04

Biological Efficacy

Cell secretory factors

Cellular senescence assay

Angiogenesis assay

Fibroblast colony-forming units (CFU-F)

Cell migration

三维干细胞大规模制备应用方案-英文-03.jpg 三维干细胞大规模制备应用方案-英文-04.jpg 三维干细胞大规模制备应用方案-英文-05.jpg 三维干细胞大规模制备应用方案-英文-06.jpg

Pre-clinical Study

Liver failure treatment

Intrauterine adhesion treatment

三维干细胞大规模制备应用方案-英文-07.png 三维干细胞大规模制备应用方案-英文-08.png

Progress of Pre-clinical and Clinical Trial on stem cells

The statistical data as of Nov 4, 2024

Indications

Mechanism study

Production process

Quality inspection

Pre-clinical animal study

IIT

Intrauterine adhesions

Intervertebral disc degeneration

Refractory wounds

Acute liver failure

Chronic kidney disease

Tendon injur

We cordially invites you to
explore the infinite potential of
stem cells and exosomes

Scan the QR Code to learn more about us
x-index2.png

电话icon(1).svg 0755 2641 2015

email.svg Enquiry@regengeek.com

dz.svg Headquarters: No. 301, Building 6, Juanhu Science and Innovation Park, No. 500, Shuiyue Pavilion East Road, Xiashi Street, Haining City, Jiaxing City, Zhejiang Province, China.

dz.svg Business center: RM. 503, Wanwei Building, No.5 5th Gongye Road, Nanshan District, Shenzhen City, Guangdong Province, China.

© 2024 REGEN-αGEEK (Haining) Biotechnology Co., Ltd.

友情链接

x-slide1.png
x-slide2.svg Click here for the latest cell industry preparation solutions