Bottlenecking problems of 2D cell culture technology
Advantages of DASEA Bio-Manufacturing platform
Subjective indicators, experience dependent
digitalization of whole process and consumables
labor intensive, low utilization rate of consumables
automatic and programable process control
insufficient use of space
3D culture, large single-batch production yield
open space operation
enclosed system, less contamination
Repeated enzyme digestion
better cell activity with biomimetic microcarriers
Expected cell harvest
Type of cultivation
Facility
Time
Labor
Reagent & consumables (thousand yuan)
Total cost (thousand yuan)
1*1010cells
2D
200㎡
1200h
10人
19.53
28.32
DASEA 3D
100㎡
120h
1人
9.60
13.30
90
%Facility
90
%Labour
80
%Time
52
%Reagents & Consumables
62
%Total Cost
细胞形态 / 活率 / 细胞数
hUMSCs 表面标记物分析
人源STR图谱鉴别
诱导体外分化能力检(三系分化)
染色体核型检查
端粒酶活性检测
软琼脂克隆形成实验
裸鼠体内接种实验
细菌 / 真菌检测
支原体检测
外源病毒检测(人源 / 动物源)
内毒素检测
裂解液残留
微载体裂解物残留检测
细胞分泌因子
细胞衰老实验
血管形成实验
成纤维细胞集落形成单位(CFU-F)
细胞迁移
Liver failure treatment
Intrauterine adhesion treatment
The statistical data as of Nov 4, 2024
Indications
Mechanism study
Production process
Quality inspection
Pre-clinical animal study
IIT
Intrauterine adhesions
Intervertebral disc degeneration
Refractory wounds
Acute liver failure
Chronic kidney disease
Tendon injur
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